| 14‑Jan‑2019 | Australian Open | Hard | F | 1 | 2 | (1)Djokovic d. (2)Rafael Nadal [ESP] | 6-3 6-2 6-3 | (ch) | 2.40 | 11.6% | 0.0% | 72.5% | 80.0% | 84.2% | 1/1 | 2:04 |
| 2‑Jul‑2018 | Wimbledon | Grass | SF | 21 | 1 | (12)Djokovic d. (2)Rafael Nadal [ESP] | 6-4 3-6 7-6(9) 3-6 10-8 | (ch) | 1.12 | 13.1% | 2.3% | 71.0% | 76.0% | 47.1% | 7/11 | 5:15 |
| 24‑May‑2015 | Roland Garros | Clay | QF | 1 | 7 | (1)Djokovic d. (6)Rafael Nadal [ESP] | 7-5 6-3 6-1 | (ch) | 1.65 | 3.8% | 0.0% | 62.5% | 76.0% | 60.0% | 3/5 | 2:26 |
| 20‑Jun‑2011 | Wimbledon | Grass | F | 2 | 1 | (2)Djokovic d. (1)Rafael Nadal [ESP] | 6-4 6-1 1-6 6-3 | (ch) | 1.16 | 7.4% | 1.1% | 72.6% | 72.5% | 53.8% | 3/6 | 2:28 |
| 26‑May‑2014 | Roland Garros | Clay | F | 2 | 1 | (1)Rafael Nadal [ESP] d. (2)Djokovic | 3-6 7-5 6-2 6-4 | (ch) | 0.84 | 8.7% | 2.4% | 65.1% | 72.0% | 36.4% | 4/10 | 3:31 |
| 16‑Jan‑2012 | Australian Open | Hard | F | 1 | 2 | (1)Djokovic d. (2)Rafael Nadal [ESP] | 5-7 6-4 6-2 6-7(5) 7-5 | (ch) | 1.21 | 5.4% | 1.2% | 59.0% | 68.4% | 63.2% | 2/6 | 5:53 |
| 25‑Jun‑2007 | Wimbledon | Grass | SF | 5 | 2 | (2)Rafael Nadal [ESP] d. (4)Djokovic | 3-6 6-1 4-1 RET | (ch) | 0.72 | 9.1% | 2.6% | 64.9% | 66.0% | 40.7% | 6/10 | 1:41 |
| 29‑Aug‑2011 | US Open | Hard | F | 1 | 2 | (1)Djokovic d. (2)Rafael Nadal [ESP] | 6-2 6-4 6-7(3) 6-1 | (ch) | 1.22 | 5.5% | 0.8% | 66.1% | 65.5% | 44.2% | 8/14 | 4:10 |
| 30‑Aug‑2010 | US Open | Hard | F | 3 | 1 | (1)Rafael Nadal [ESP] d. (3)Djokovic | 6-4 5-7 6-4 6-2 | (ch) | 0.77 | 3.5% | 2.8% | 65.7% | 64.9% | 44.9% | 20/25 | 3:43 |
| 31‑May‑2021 | Roland Garros | Clay | SF | 1 | 3 | (1)Djokovic d. (3)Rafael Nadal [ESP] | 3-6 6-3 7-6(4) 6-2 | (ch) | 1.17 | 4.5% | 2.3% | 63.9% | 64.7% | 50.0% | 10/16 | 4:11 |
| 27‑May‑2013 | Roland Garros | Clay | SF | 1 | 4 | (3)Rafael Nadal [ESP] d. (1)Djokovic | 6-4 3-6 6-1 6-7(3) 9-7 | (ch) | 0.82 | 2.9% | 1.1% | 67.4% | 64.4% | 52.6% | 8/16 | 4:37 |
| 23‑May‑2022 | Roland Garros | Clay | QF | 1 | 5 | (5)Rafael Nadal [ESP] d. (1)Djokovic | 6-2 4-6 6-2 7-6(4) | (ch) | 0.85 | 3.6% | 2.9% | 69.3% | 63.9% | 41.9% | 10/17 | 4:12 |
| 27‑May‑2012 | Roland Garros | Clay | F | 1 | 2 | (2)Rafael Nadal [ESP] d. (1)Djokovic | 6-4 6-3 2-6 7-5 | (ch) | 0.91 | 2.4% | 3.3% | 59.3% | 61.6% | 44.0% | 8/17 | 3:49 |
| 26‑Aug‑2013 | US Open | Hard | F | 1 | 2 | (2)Rafael Nadal [ESP] d. (1)Djokovic | 6-2 3-6 6-4 6-1 | (ch) | 0.84 | 5.9% | 2.0% | 67.6% | 58.0% | 48.5% | 5/11 | 3:21 |
| 25‑May‑2008 | Roland Garros | Clay | SF | 3 | 2 | (2)Rafael Nadal [ESP] d. (3)Djokovic | 6-4 6-2 7-6(3) | (ch) | 0.78 | 2.0% | 1.0% | 54.0% | 57.4% | 58.7% | 9/14 | 2:49 |
| 28‑May‑2007 | Roland Garros | Clay | SF | 6 | 2 | (2)Rafael Nadal [ESP] d. (6)Djokovic | 7-5 6-4 6-2 | (ch) | 0.62 | 3.2% | 1.1% | 71.6% | 57.4% | 37.0% | 3/9 | 2:28 |
| 29‑May‑2006 | Roland Garros | Clay | QF | 63 | 2 | (2)Rafael Nadal [ESP] d. Djokovic | 6-4 6-4 RET | (ch) | 0.69 | 3.0% | 4.5% | 73.1% | 55.1% | 22.2% | 2/7 | 1:54 |
| 28‑Sep‑2020 | Roland Garros | Clay | F | 1 | 2 | (1)Rafael Nadal [ESP] d. (2)Djokovic | 6-0 6-2 7-5 | (ch) | 0.66 | 1.0% | 4.0% | 66.7% | 50.0% | 48.5% | 11/18 | 2:41 |
