| 14‑Nov‑2016 | Tour Finals | Hard | RR | 9 | 6 | (8)Thiem d. (6)Gael Monfils [FRA] | 6-3 1-6 6-4 | (ch) | 0.90 | 5.2% | 1.3% | 61.0% | 72.3% | 40.0% | 0/3 | |
| 14‑Nov‑2016 | Tour Finals | Hard | RR | 9 | 2 | (2)Novak Djokovic [SRB] d. (8)Thiem | 6-7(10) 6-0 6-2 | (ch) | 0.60 | 4.2% | 3.1% | 66.7% | 67.2% | 34.4% | 1/6 | 2:02 |
| 3‑Oct‑2016 | Beijing | Hard | R32 | 10 | 24 | Alexander Zverev [GER] d. (4)Thiem | 4-6 6-1 6-3 | | 0.84 | 7.2% | 10.8% | 60.2% | 62.0% | 45.5% | 9/14 | 1:51 |
| 19‑Sep‑2016 | Metz | Hard | SF | 10 | 28 | (1)Thiem d. (4)Gilles Simon [FRA] | 4-6 7-5 6-3 | | 1.14 | 10.9% | 1.1% | 64.1% | 76.3% | 42.4% | 4/8 | 2:17 |
| 29‑Aug‑2016 | US Open | Hard | R128 | 10 | 66 | (8)Thiem d. John Millman [AUS] | 6-3 2-6 5-7 6-4 6-3 | | 1.02 | 6.8% | 2.1% | 67.8% | 62.6% | 59.6% | 5/11 | 3:05 |
| 6‑Jun‑2016 | Stuttgart | Grass | F | 7 | 26 | (3)Thiem d. (7)Philipp Kohlschreiber [GER] | 6-7(2) 6-4 6-4 | (ch) | 1.14 | 11.5% | 5.8% | 48.1% | 90.0% | 51.9% | 5/5 | 2:11 |
| 6‑Jun‑2016 | Stuttgart | Grass | SF | 7 | 3 | (3)Thiem d. (1)Roger Federer [SUI] | 3-6 7-6(7) 6-4 | (ch) | 1.01 | 8.8% | 5.9% | 60.8% | 74.2% | 47.5% | 5/8 | 1:57 |
| 6‑Jun‑2016 | Stuttgart | Grass | QF | 7 | 76 | (3)Thiem d. Mikhail Youzhny [RUS] | 3-6 6-4 7-5 | | 1.10 | 13.6% | 11.1% | 60.5% | 85.7% | 46.9% | 3/5 | 1:50 |
| 16‑May‑2016 | Nice | Clay | F | 15 | 48 | (1)Thiem d. (8)Alexander Zverev [GER] | 6-4 3-6 6-0 | (ch) | 1.33 | 6.3% | 6.3% | 56.3% | 71.1% | 48.6% | 5/9 | 1:39 |
| 9‑May‑2016 | Rome Masters | Clay | R64 | 15 | 28 | (13)Thiem d. Alexandr Dolgopolov [UKR] | 6-3 3-6 6-4 | | 1.24 | 7.9% | 2.6% | 56.6% | 83.7% | 57.6% | 1/2 | 1:41 |
| 25‑Apr‑2016 | Munich | Clay | F | 15 | 27 | (4)Philipp Kohlschreiber [GER] d. (3)Thiem | 7-6(7) 4-6 7-6(4) | (ch) | 0.89 | 6.3% | 2.4% | 69.0% | 63.2% | 46.2% | 6/10 | 2:31 |
| 25‑Apr‑2016 | Munich | Clay | SF | 15 | 49 | (3)Thiem d. (8)Alexander Zverev [GER] | 4-6 6-2 6-3 | | 1.18 | 6.5% | 9.7% | 58.1% | 75.9% | 43.6% | 8/11 | 2:00 |
| 25‑Apr‑2016 | Munich | Clay | QF | 15 | 75 | (3)Thiem d. Ivan Dodig [CRO] | 6-4 4-6 6-3 | | 1.33 | 10.1% | 2.5% | 65.8% | 76.9% | 59.3% | 2/4 | 2:12 |
| 11‑Apr‑2016 | Monte Carlo Masters | Clay | R32 | 14 | 90 | (12)Thiem d. (Q)Taro Daniel [JPN] | 4-6 6-2 6-0 | (ch) | 1.29 | 8.3% | 5.6% | 59.7% | 72.1% | 55.2% | 2/4 | 1:43 |
| 11‑Apr‑2016 | Monte Carlo Masters | Clay | R64 | 14 | 115 | (12)Thiem d. (Q)Jan Lennard Struff [GER] | 1-6 6-3 6-4 | | 0.72 | 6.4% | 3.2% | 66.0% | 66.1% | 50.0% | 5/7 | 1:36 |
| 7‑Mar‑2016 | Indian Wells Masters | Hard | R32 | 13 | 24 | (11)Thiem d. (21)Jack Sock [USA] | 7-5 6-7(5) 6-1 | | 1.34 | 7.8% | 3.3% | 60.0% | 72.2% | 52.8% | 4/7 | 2:14 |
| 4‑Mar‑2016 | Davis Cup G1 R1: POR vs AUT | Hard | RR | 14 | 121 | Thiem d. Gastao Elias [POR] | 3-6 7-5 6-3 1-6 7-6(6) | | 1.15 | 3.0% | 3.0% | 59.0% | 77.2% | 63.6% | 4/8 | 3:28 |
| 4‑Mar‑2016 | Davis Cup G1 R1: POR vs AUT | Hard | RR | 14 | 37 | Thiem d. Joao Sousa [POR] | 6-2 6-4 6-2 | | 1.74 | 5.6% | 1.4% | 66.2% | 85.1% | 58.3% | 1/1 | 1:34 |
| 22‑Feb‑2016 | Acapulco | Hard | F | 15 | 21 | (4)Thiem d. (5)Bernard Tomic [AUS] | 7-6(6) 4-6 6-3 | (ch) | 1.41 | 25.6% | 1.2% | 77.9% | 82.1% | 42.1% | 0/3 | 1:55 |
| 22‑Feb‑2016 | Acapulco | Hard | R16 | 15 | 1045 | (4)Thiem d. Dmitry Tursunov [RUS] | 6-7(5) 6-3 6-4 | | 1.15 | 11.1% | 1.1% | 57.8% | 80.8% | 60.5% | 1/2 | 1:59 |
| 8‑Feb‑2016 | Buenos Aires | Clay | F | 19 | 72 | (5)Thiem d. Nicolas Almagro [ESP] | 7-6(2) 3-6 7-6(4) | (ch) | 1.06 | 8.0% | 4.4% | 74.3% | 76.2% | 41.4% | 8/11 | 2:28 |
| 8‑Feb‑2016 | Buenos Aires | Clay | SF | 19 | 5 | (5)Thiem d. (1)Rafael Nadal [ESP] | 6-4 4-6 7-6(4) | (ch) | 1.05 | 8.0% | 0.9% | 66.1% | 67.6% | 60.5% | 4/7 | 2:50 |
| 8‑Feb‑2016 | Buenos Aires | Clay | R16 | 19 | 142 | (5)Thiem d. (Q)Gastao Elias [POR] | 3-6 7-6(7) 6-3 | | 1.25 | 6.6% | 3.3% | 69.2% | 74.6% | 64.3% | 0/3 | 2:09 |
| 8‑Feb‑2016 | Buenos Aires | Clay | R32 | 19 | 64 | (5)Thiem d. Pablo Carreno Busta [ESP] | 6-0 3-6 6-3 | | 1.35 | 5.8% | 1.4% | 72.5% | 74.0% | 57.9% | 3/5 | 1:20 |
| 4‑Jan‑2016 | Brisbane | Hard | QF | 20 | 13 | (8)Thiem d. (3)Marin Cilic [CRO] | 2-6 7-6(4) 6-4 | | 1.12 | 7.1% | 0.0% | 65.5% | 74.5% | 69.0% | 0/2 | 1:59 |
| 4‑Jan‑2016 | Brisbane | Hard | R32 | 20 | 120 | (8)Thiem d. (WC)James Duckworth [AUS] | 3-6 6-4 6-3 | | 1.25 | 5.0% | 2.5% | 60.0% | 72.9% | 65.6% | 2/4 | 1:53 |
