| 2‑Oct‑2017 | Tokyo | Hard | R32 | 49 | 139 | (Q)Matthew Ebden [AUS] d. Karlovic | 6-4 6-3 | | 0.66 | 25.0% | 11.5% | 65.4% | 76.5% | 33.3% | 2/5 | 1:07 |
| 3‑Oct‑2016 | Tokyo | Hard | QF | 21 | 8 | (2)Gael Monfils [FRA] d. (7)Karlovic | 7-6(6) 7-6(6) | | 0.79 | 12.2% | 5.4% | 67.6% | 80.0% | 66.7% | 2/3 | 1:31 |
| 3‑Oct‑2016 | Tokyo | Hard | R16 | 21 | 173 | (7)Karlovic d. (PR)Janko Tipsarevic [SRB] | 7-6(9) 7-6(5) | (ch) | 1.06 | 29.3% | 3.7% | 65.9% | 79.6% | 64.3% | 3/4 | 1:48 |
| 3‑Oct‑2016 | Tokyo | Hard | R32 | 21 | 47 | (7)Karlovic d. Federico Delbonis [ARG] | 7-6(6) 6-7(6) 7-6(5) | | 0.86 | 26.0% | 6.5% | 69.9% | 84.9% | 40.5% | 3/4 | 2:36 |
| 1‑Oct‑2012 | Tokyo | Hard | R32 | 79 | 3 | (1)Andy Murray [GBR] d. (LL)Karlovic | 7-6(7) 6-4 | | 0.51 | 24.7% | 2.7% | 64.4% | 78.7% | 53.8% | 5/6 | 1:38 |
| 1‑Oct‑2012 | Tokyo | Hard | Q2 | 79 | 143 | (7)Marco Chiudinelli [SUI] d. (2)Karlovic | 6-3 6-7(6) 7-6(5) | | 0.67 | 21.8% | 2.7% | 63.6% | 85.7% | 47.5% | 3/4 | 2:39 |
| 1‑Oct‑2012 | Tokyo | Hard | Q1 | 79 | 340 | (2)Karlovic d. Yasutaka Uchiyama [JPN] | 6-4 6-2 | | 2.73 | 32.6% | 4.7% | 60.5% | 92.3% | 70.6% | 0/0 | 1:14 |
| 1‑Oct‑2007 | Tokyo | Hard | SF | 28 | 8 | (1)David Ferrer [ESP] d. (7)Karlovic | 7-6(3) 6-3 | | 0.53 | 14.1% | 1.4% | 66.2% | 78.7% | 37.5% | 2/3 | 1:21 |
| 1‑Oct‑2007 | Tokyo | Hard | QF | 28 | 19 | (7)Karlovic d. (4)Lleyton Hewitt [AUS] | 7-6(5) 7-6(6) | | 1.12 | 31.3% | 2.5% | 70.0% | 91.1% | 41.7% | 4/4 | 1:51 |
| 1‑Oct‑2007 | Tokyo | Hard | R16 | 28 | 39 | (7)Karlovic d. (9)Hyung Taik Lee [KOR] | 7-6(6) 6-7(8) 7-6(8) | | 0.91 | 26.9% | 1.5% | 71.5% | 80.6% | 59.5% | 4/4 | 2:39 |
| 1‑Oct‑2007 | Tokyo | Hard | R32 | 28 | 58 | (7)Karlovic d. Benjamin Becker [GER] | 6-4 6-3 | | 1.32 | 22.4% | 1.7% | 72.4% | 81.0% | 56.3% | 3/3 | 1:06 |
| 29‑Sep‑2003 | Tokyo | Hard | R32 | 76 | 10 | (2)Sebastien Grosjean [FRA] d. Karlovic | 6-3 7-6(8) | | 0.71 | 13.8% | 9.2% | 60.0% | 87.2% | 42.3% | 3/4 | 1:31 |
| 29‑Sep‑2003 | Tokyo | Hard | R64 | 76 | 78 | Karlovic d. Robin Soderling [SWE] | 6-4 6-4 | | 1.61 | 14.0% | 7.0% | 63.2% | 86.1% | 61.9% | 2/2 | 1:09 |
