| 14‑Oct‑2024 | Antwerp | Hard | R32 | 81 | 54 | Roberto Carballes Baena [ESP] d. Koepfer | 6-4 6-0 | | 0.63 | 2.0% | 6.0% | 60.0% | 60.0% | 25.0% | 1/6 | 1:13 |
| 18‑Mar‑2024 | Miami Masters | Hard | R16 | 50 | 4 | (3)Daniil Medvedev [RUS] d. Koepfer | 7-6(5) 6-0 | | 0.71 | 7.2% | 2.9% | 78.3% | 59.3% | 26.7% | 5/9 | 1:29 |
| 4‑Dec‑2021 | Davis Cup Finals SF: RTF vs GER | Hard | RR | 54 | 5 | Andrey Rublev [RUS] d. Koepfer | 6-4 6-0 | | 0.48 | 4.7% | 4.7% | 48.8% | 57.1% | 45.5% | 0/4 | 0:48 |
| 4‑Oct‑2021 | Indian Wells Masters | Hard | R128 | 64 | 91 | Emil Ruusuvuori [FIN] d. Koepfer | 6-7(3) 6-2 6-0 | | 0.78 | 2.4% | 8.2% | 54.1% | 54.3% | 43.6% | 4/11 | 2:14 |
| 8‑Feb‑2021 | Australian Open | Hard | R64 | 70 | 3 | (3)Dominic Thiem [AUT] d. Koepfer | 6-4 6-0 6-2 | | 0.48 | 1.4% | 4.1% | 58.1% | 60.5% | 35.5% | 6/12 | 1:39 |
| 1‑Jul‑2019 | Wimbledon | Grass | R64 | 130 | 24 | (24)Diego Schwartzman [ARG] d. Koepfer | 6-0 6-3 7-5 | | 0.66 | 6.6% | 6.6% | 56.6% | 66.7% | 32.6% | 9/15 | 1:53 |
