| 5‑Aug‑2024 | Canada Masters | Hard | QF | 8 | 1 | (5)Rublev d. (1)Jannik Sinner [ITA] | 6-3 1-6 6-2 | (ch) | 1.04 | 5.1% | 1.3% | 62.0% | 73.5% | 46.7% | 10/12 | 1:47 |
| 1‑Jan‑2024 | Hong Kong | Hard | QF | 5 | 36 | (1)Rublev d. (8)Arthur Fils [FRA] | 6-4 1-6 6-2 | (ch) | 1.45 | 12.3% | 0.0% | 63.1% | 75.6% | 62.5% | 4/6 | 1:52 |
| 3‑Jul‑2023 | Wimbledon | Grass | QF | 7 | 2 | (2)Novak Djokovic [SRB] d. (7)Rublev | 4-6 6-1 6-4 6-3 | | 0.75 | 5.8% | 1.9% | 58.3% | 73.3% | 44.2% | 7/12 | 2:48 |
| 27‑Feb‑2023 | Dubai | Hard | R16 | 6 | 29 | (2)Rublev d. Alejandro Davidovich Fokina [ESP] | 1-6 7-6(6) 7-6(3) | (ch) | 1.02 | 11.9% | 2.0% | 62.4% | 76.2% | 57.9% | 2/4 | 2:25 |
| 20‑Feb‑2023 | Doha | Hard | R16 | 5 | 40 | (1)Rublev d. Tallon Griekspoor [NED] | 1-6 6-1 7-6(6) | | 1.16 | 13.0% | 3.9% | 59.7% | 78.3% | 51.6% | 2/5 | 1:54 |
| 16‑Jan‑2023 | Australian Open | Hard | QF | 6 | 5 | (4)Novak Djokovic [SRB] d. (5)Rublev | 6-1 6-2 6-4 | (ch) | 0.64 | 6.5% | 3.3% | 69.6% | 60.9% | 32.1% | 9/14 | 2:03 |
| 14‑Nov‑2022 | Tour Finals | Hard | RR | 7 | 8 | (7)Novak Djokovic [SRB] d. (6)Rublev | 6-4 6-1 | (ch) | 0.36 | 17.9% | 1.8% | 55.4% | 71.0% | 36.0% | 1/4 | 1:07 |
| 23‑May‑2022 | Roland Garros | Clay | R16 | 7 | 12 | (7)Rublev d. (11)Jannik Sinner [ITA] | 1-6 6-4 2-0 RET | | 1.26 | 8.3% | 0.0% | 62.5% | 83.3% | 44.4% | 0/2 | |
| 11‑Apr‑2022 | Monte Carlo Masters | Clay | R16 | 8 | 12 | (9)Jannik Sinner [ITA] d. (5)Rublev | 5-7 6-1 6-3 | (ch) | 0.77 | 0.0% | 7.0% | 65.0% | 60.0% | 34.3% | 5/12 | 2:20 |
| 14‑Feb‑2022 | Marseille | Hard | QF | 7 | 154 | (2)Rublev d. (WC)Lucas Pouille [FRA] | 6-3 1-6 6-2 | | 1.26 | 11.1% | 3.2% | 54.0% | 67.6% | 62.1% | 1/4 | 1:41 |
| 30‑Aug‑2021 | US Open | Hard | R32 | 7 | 50 | Frances Tiafoe [USA] d. (5)Rublev | 4-6 6-3 7-6(6) 4-6 6-1 | | 1.08 | 17.4% | 4.9% | 61.1% | 77.3% | 42.9% | 9/14 | 3:45 |
| 16‑Nov‑2020 | Tour Finals | Hard | RR | 8 | 6 | (6)Stefanos Tsitsipas [GRE] d. (7)Rublev | 6-1 4-6 7-6(6) | | 0.74 | 6.3% | 2.1% | 62.1% | 74.6% | 47.2% | 7/9 | 1:55 |
| 26‑Aug‑2019 | US Open | Hard | R16 | 43 | 25 | (24)Matteo Berrettini [ITA] d. Rublev | 6-1 6-4 7-6(6) | | 0.69 | 7.7% | 1.9% | 55.8% | 67.2% | 45.7% | 6/10 | 2:11 |
| 18‑Feb‑2019 | Marseille | Hard | QF | 115 | 50 | Mikhail Kukushkin [KAZ] d. Rublev | 6-4 6-1 | | 0.68 | 12.8% | 2.6% | 53.8% | 71.4% | 33.3% | 3/7 | 1:05 |
| 7‑Jan‑2019 | Sydney | Hard | R16 | 84 | 75 | (Q)Yoshihito Nishioka [JPN] d. (Q)Rublev | 6-3 6-1 | | 0.69 | 6.4% | 17.0% | 53.2% | 56.0% | 31.8% | 4/9 | 1:04 |
| 27‑Aug‑2018 | US Open | Hard | R128 | 38 | 46 | Jeremy Chardy [FRA] d. Rublev | 6-2 4-6 6-4 6-1 | | 0.75 | 4.5% | 11.6% | 50.9% | 71.9% | 32.7% | 7/14 | 2:28 |
| 2‑Oct‑2017 | Beijing | Hard | R16 | 39 | 20 | Rublev d. (7)Tomas Berdych [CZE] | 1-6 6-4 6-1 | | 1.09 | 6.8% | 11.4% | 46.6% | 65.9% | 46.8% | 5/9 | 1:48 |
| 25‑Sep‑2017 | Chengdu | Hard | R16 | 37 | 63 | Yen Hsun Lu [TPE] d. (4)Rublev | 6-2 6-1 | | 0.49 | 11.1% | 2.2% | 40.0% | 72.2% | 37.0% | 8/12 | 0:53 |
| 28‑Aug‑2017 | US Open | Hard | QF | 53 | 1 | (1)Rafael Nadal [ESP] d. Rublev | 6-1 6-2 6-2 | | 0.46 | 1.2% | 8.5% | 62.2% | 54.9% | 29.0% | 11/18 | 1:36 |
| 21‑Aug‑2017 | Winston-Salem | Hard | R32 | 54 | 49 | (13)Hyeon Chung [KOR] d. Rublev | 5-7 6-1 6-1 | | 0.69 | 9.3% | 7.0% | 57.0% | 57.1% | 45.9% | 4/10 | 1:48 |
| 24‑Jul‑2017 | Hamburg | Clay | R32 | 49 | 58 | Philipp Kohlschreiber [GER] d. (SE)Rublev | 6-3 6-1 | | 0.63 | 1.9% | 3.8% | 54.7% | 58.6% | 25.0% | 4/9 | 1:11 |
| 3‑Jul‑2017 | Wimbledon | Grass | R128 | 95 | 155 | (Q)Rublev d. (Q)Stefano Travaglia [ITA] | 6-7(3) 6-3 7-5 1-6 7-5 | | 1.06 | 6.0% | 3.0% | 63.7% | 71.0% | 50.8% | 5/10 | 3:27 |
| 20‑Feb‑2017 | Marseille | Hard | R32 | 111 | 93 | Illya Marchenko [UKR] d. (Q)Rublev | 6-1 7-6(6) | | 0.71 | 7.0% | 2.8% | 50.7% | 75.0% | 34.3% | 4/8 | 1:36 |
| 11‑Apr‑2016 | Monte Carlo Masters | Clay | R64 | 157 | 54 | Alexander Zverev [GER] d. (WC)Rublev | 6-1 6-3 | | 0.51 | 0.0% | 4.3% | 52.2% | 45.8% | 59.1% | 2/6 | 1:00 |
| 21‑Sep‑2015 | St. Petersburg | Hard | R32 | 178 | 63 | Simone Bolelli [ITA] d. (WC)Rublev | 4-6 6-3 6-1 | | 0.85 | 7.1% | 7.1% | 59.6% | 62.7% | 45.0% | 10/15 | |
| 17‑May‑2015 | Geneva | Clay | R16 | 229 | 10 | (2)Marin Cilic [CRO] d. (WC)Rublev | 4-6 7-6(7) 6-1 | | 0.75 | 5.4% | 0.0% | 64.1% | 71.2% | 54.5% | 1/4 | 1:41 |
| 20‑Apr‑2015 | Barcelona | Clay | R32 | 329 | 30 | (13)Fabio Fognini [ITA] d. (Q)Rublev | 3-6 6-4 6-1 | | 0.86 | 1.2% | 2.5% | 49.4% | 65.0% | 39.0% | 4/10 | 1:44 |
| 25‑Mar‑2015 | Miami Masters | Hard | R128 | 389 | 54 | (WC)Rublev d. Pablo Carreno Busta [ESP] | 1-6 6-1 6-4 | | 1.02 | 5.3% | 6.4% | 60.6% | 66.7% | 45.9% | 8/11 | 1:51 |
| 16‑Feb‑2015 | Delray Beach | Hard | R32 | 370 | 90 | (WC)Rublev d. Dudi Sela [ISR] | 6-4 1-6 6-3 | | 0.98 | 2.5% | 5.0% | 60.0% | 64.6% | 65.6% | 5/7 | 1:33 |
