| 5‑Mar‑2025 | Indian Wells Masters | Hard | R16 | 12 | 33 | (11)Shelton d. (32)Brandon Nakashima [USA] | 7-6(6) 6-1 | | 1.48 | 9.8% | 1.6% | 65.6% | 72.5% | 66.7% | 3/4 | 1:34 |
| 25‑Sep‑2024 | Tokyo | Hard | R32 | 17 | 306 | (8)Shelton d. (PR)Reilly Opelka [USA] | 3-6 6-1 6-4 | | 1.21 | 11.1% | 4.2% | 72.2% | 76.9% | 50.0% | 3/5 | 1:46 |
| 15‑Jan‑2024 | Australian Open | Hard | R32 | 16 | 19 | (20)Adrian Mannarino [FRA] d. (16)Shelton | 7-6(4) 1-6 6-7(2) 6-3 6-4 | (ch) | 1.06 | 10.1% | 2.2% | 71.9% | 67.2% | 48.0% | 11/17 | 4:46 |
| 15‑Jan‑2024 | Australian Open | Hard | R64 | 16 | 68 | (16)Shelton d. Christopher Oconnell [AUS] | 6-4 6-1 3-6 7-6(5) | | 1.34 | 14.9% | 3.5% | 66.7% | 73.7% | 63.2% | 3/5 | 2:51 |
| 16‑Oct‑2023 | Tokyo | Hard | F | 19 | 50 | Shelton d. Aslan Karatsev [RUS] | 7-5 6-1 | (ch) | 2.02 | 6.0% | 2.0% | 80.0% | 80.0% | 70.0% | 1/1 | 1:22 |
| 8‑May‑2023 | Rome Masters | Clay | R64 | 35 | 49 | Alexander Bublik [KAZ] d. (28)Shelton | 6-4 1-6 6-2 | | 0.83 | 12.2% | 6.1% | 43.9% | 80.6% | 52.2% | 7/10 | 1:52 |
| 6‑Mar‑2023 | Indian Wells Masters | Hard | R128 | 41 | 88 | Shelton d. Fabio Fognini [ITA] | 6-4 6-1 | | 1.31 | 7.9% | 7.9% | 68.3% | 65.1% | 55.0% | 4/5 | 1:10 |
| 9‑Jan‑2023 | Auckland | Hard | R32 | 92 | 41 | (WC)Shelton d. (7)Sebastian Baez [ARG] | 7-6(1) 6-1 | (ch) | 2.08 | 17.6% | 2.0% | 66.7% | 82.4% | 70.6% | 2/2 | 1:22 |
