| 6‑Oct‑2003 | Lyon | Carpet | QF | 60 | 6 | (1)Rainer Schuettler [GER] d. (Q)Malisse | 7-6(2) 6-4 | | 0.70 | 1.3% | 1.3% | 60.5% | 58.7% | 50.0% | 6/10 | 1:35 |
| 6‑Oct‑2003 | Lyon | Carpet | R16 | 60 | 163 | (Q)Malisse d. (Q)Thomas Enqvist [SWE] | 6-3 6-4 | | 1.44 | 9.8% | 7.8% | 54.9% | 64.3% | 65.2% | 1/3 | 1:19 |
| 6‑Oct‑2003 | Lyon | Carpet | R32 | 60 | 109 | (Q)Malisse d. Andrei Pavel [ROU] | 5-7 6-3 6-4 | | 1.33 | 12.2% | 3.3% | 57.8% | 86.5% | 57.9% | 1/2 | 1:48 |
| 25‑Aug‑2003 | US Open | Hard | R16 | 67 | 4 | (4)Andy Roddick [USA] d. Malisse | 6-3 6-4 7-6(5) | | 0.53 | 11.2% | 3.7% | 52.3% | 78.6% | 49.0% | 6/8 | 1:59 |
| 25‑Aug‑2003 | US Open | Hard | R32 | 67 | 174 | Malisse d. (Q)Dmitry Tursunov [RUS] | 7-5 6-4 7-6(8) | | 1.28 | 8.7% | 1.9% | 49.5% | 76.5% | 51.9% | 1/5 | 1:59 |
| 25‑Aug‑2003 | US Open | Hard | R64 | 67 | 19 | Malisse d. (19)Agustin Calleri [ARG] | 6-2 6-7(3) 6-3 3-6 6-3 | | 1.09 | 7.5% | 4.5% | 43.3% | 86.2% | 48.7% | 4/9 | 2:59 |
| 25‑Aug‑2003 | US Open | Hard | R128 | 67 | 48 | Malisse d. Olivier Rochus [BEL] | 6-3 6-4 6-2 | | 1.65 | 23.5% | 3.7% | 53.1% | 76.7% | 65.8% | 1/2 | 1:39 |
| 11‑Aug‑2003 | Cincinnati Masters | Hard | R32 | 68 | 41 | Mardy Fish [USA] d. Malisse | 7-5 6-7(5) 6-1 | | 0.80 | 14.7% | 4.9% | 54.9% | 85.7% | 41.3% | 3/6 | 2:15 |
| 11‑Aug‑2003 | Cincinnati Masters | Hard | R64 | 68 | 6 | Malisse d. (5)Lleyton Hewitt [AUS] | 3-6 6-4 6-2 | | 1.08 | 12.5% | 7.5% | 36.3% | 79.3% | 49.0% | 4/8 | 1:43 |
| 4‑Aug‑2003 | Canada Masters | Hard | R64 | 62 | 7 | (6)Andy Roddick [USA] d. Malisse | 3-6 6-0 6-2 | | 0.67 | 7.0% | 4.2% | 36.6% | 69.2% | 46.7% | 3/8 | 1:30 |
| 28‑Jul‑2003 | Los Angeles | Hard | R32 | 64 | 9 | (2)Sebastien Grosjean [FRA] d. Malisse | 4-6 7-5 6-3 | | 1.08 | 11.4% | 3.4% | 67.0% | 78.0% | 55.2% | 5/7 | 1:55 |
| 21‑Jul‑2003 | Indianapolis | Hard | QF | 68 | 6 | (1)Andy Roddick [USA] d. (9)Malisse | 6-4 6-1 | | 0.53 | 10.6% | 0.0% | 59.6% | 67.9% | 36.8% | 3/6 | 0:59 |
| 21‑Jul‑2003 | Indianapolis | Hard | R16 | 68 | 39 | (9)Malisse d. (5)Jan Michael Gambill [USA] | 6-4 6-2 | | 1.67 | 16.7% | 2.1% | 52.1% | 84.0% | 60.9% | 1/2 | 1:05 |
| 21‑Jul‑2003 | Indianapolis | Hard | R32 | 68 | 485 | (9)Malisse d. (WC)Rajeev Ram [USA] | 6-2 6-4 | | 1.90 | 17.8% | 2.2% | 62.2% | 78.6% | 70.6% | 1/2 | 1:04 |
| 23‑Jun‑2003 | Wimbledon | Grass | R128 | 31 | 124 | (Q)Cyril Saulnier [FRA] d. (14)Malisse | 6-4 6-3 6-2 | | 0.66 | 7.6% | 3.8% | 45.6% | 69.4% | 53.5% | 3/7 | 1:33 |
| 9‑Jun‑2003 | Queen's Club | Grass | QF | 32 | 2 | (2)Andre Agassi [USA] d. (8)Malisse | 6-4 7-5 | | 0.69 | 29.1% | 3.6% | 58.2% | 84.4% | 52.2% | 1/3 | 1:01 |
| 9‑Jun‑2003 | Queen's Club | Grass | R16 | 32 | 108 | (8)Malisse d. Marc Rosset [SUI] | 7-6(4) 7-5 | | 1.27 | 16.4% | 9.0% | 52.2% | 82.9% | 56.3% | 0/2 | 1:27 |
| 9‑Jun‑2003 | Queen's Club | Grass | R32 | 32 | 208 | (8)Malisse d. (Q)Ivo Karlovic [CRO] | 6-3 7-6(3) | | 3.15 | 14.3% | 3.6% | 53.6% | 96.7% | 76.9% | 0/0 | 1:17 |
| 26‑May‑2003 | Roland Garros | Clay | R32 | 29 | 2 | (2)Andre Agassi [USA] d. (26)Malisse | 6-4 7-5 7-5 | | 0.89 | 13.1% | 5.1% | 46.5% | 76.1% | 52.8% | 6/10 | 2:09 |
| 26‑May‑2003 | Roland Garros | Clay | R64 | 29 | 72 | (26)Malisse d. Stefan Koubek [AUT] | 3-6 4-6 6-4 7-5 8-6 | | 1.00 | 4.0% | 2.8% | 52.0% | 67.4% | 44.7% | 15/25 | 3:54 |
| 26‑May‑2003 | Roland Garros | Clay | R128 | 29 | 206 | (26)Malisse d. (Q)Alex Calatrava [ESP] | 7-5 6-4 6-2 | | 1.50 | 18.5% | 2.2% | 60.9% | 80.4% | 50.0% | 4/6 | 2:17 |
| 12‑May‑2003 | Hamburg Masters | Clay | R32 | 30 | 67 | Mark Philippoussis [AUS] d. Malisse | 6-3 7-6(4) | | 0.79 | 7.9% | 5.3% | 52.6% | 67.5% | 38.9% | 5/9 | 1:38 |
| 12‑May‑2003 | Hamburg Masters | Clay | R64 | 30 | 17 | Malisse d. (13)Alex Corretja [ESP] | 7-6(3) 4-6 6-3 | | 1.10 | 11.5% | 3.1% | 46.9% | 73.3% | 47.1% | 4/9 | 2:23 |
| 5‑May‑2003 | Rome Masters | Clay | R64 | 26 | 46 | Ivan Ljubicic [CRO] d. Malisse | 6-2 6-4 | | 0.62 | 4.5% | 3.0% | 45.5% | 70.0% | 44.4% | 3/6 | 1:14 |
| 21‑Apr‑2003 | Barcelona | Clay | R32 | 28 | 35 | Jarkko Nieminen [FIN] d. (14)Malisse | 6-3 4-6 6-0 | | 0.80 | 4.3% | 4.3% | 67.0% | 50.8% | 51.6% | 12/18 | 1:39 |
| 21‑Apr‑2003 | Barcelona | Clay | R64 | 28 | 94 | (14)Malisse d. Hicham Arazi [MAR] | 7-5 RET | | 1.43 | 11.8% | 0.0% | 58.8% | 80.0% | 64.3% | 1/1 | 0:40 |
| 14‑Apr‑2003 | Monte Carlo Masters | Clay | R64 | 28 | 4 | (2)Carlos Moya [ESP] d. Malisse | 6-3 6-3 | | 0.76 | 1.9% | 3.8% | 49.1% | 53.8% | 37.0% | 7/13 | 1:13 |
| 17‑Mar‑2003 | Miami Masters | Hard | R64 | 28 | 59 | Hyung Taik Lee [KOR] d. (25)Malisse | 6-7(6) 6-2 6-1 | | 0.69 | 12.1% | 6.1% | 47.5% | 66.0% | 40.4% | 4/11 | 2:00 |
| 10‑Mar‑2003 | Indian Wells Masters | Hard | R32 | 31 | 11 | (11)Sebastien Grosjean [FRA] d. Malisse | 6-3 6-3 | | 0.71 | 0.0% | 8.6% | 44.8% | 65.4% | 56.3% | 2/5 | 1:18 |
| 10‑Mar‑2003 | Indian Wells Masters | Hard | R64 | 31 | 50 | Malisse d. David Ferrer [ESP] | 6-1 6-0 | | 2.87 | 15.6% | 0.0% | 62.5% | 80.0% | 75.0% | 0/0 | 0:43 |
| 3‑Mar‑2003 | Scottsdale | Hard | R32 | 25 | 114 | Cecil Mamiit [PHI] d. (8)Malisse | 7-6(5) 7-6(3) | | 1.02 | 6.7% | 3.4% | 51.7% | 71.7% | 46.5% | 7/10 | 2:02 |
| 17‑Feb‑2003 | Rotterdam | Hard | R32 | 24 | 7 | (3)Marat Safin [RUS] d. Malisse | 7-5 6-3 | | 0.66 | 4.9% | 4.9% | 52.5% | 75.0% | 48.3% | 3/6 | 1:11 |
| 7‑Feb‑2003 | Davis Cup WG R1: ESP vs BEL | Clay | RR | 23 | 4 | Carlos Moya [ESP] d. Malisse | 7-6(2) 6-1 7-6(5) | | | | | | | | | |
| 27‑Jan‑2003 | Milan | Carpet | R16 | 23 | 162 | (Q)Julien Varlet [FRA] d. (4)Malisse | 2-6 7-5 7-6(6) | | 1.44 | 12.2% | 2.2% | 58.9% | 88.7% | 51.4% | 1/3 | 2:05 |
| 27‑Jan‑2003 | Milan | Carpet | R32 | 23 | 65 | (4)Malisse d. Andre Sa [BRA] | 6-4 6-4 | | 1.17 | 18.2% | 1.3% | 59.7% | 69.6% | 54.8% | 5/6 | 1:22 |
| 13‑Jan‑2003 | Australian Open | Hard | R32 | 23 | 12 | (10)David Nalbandian [ARG] d. (20)Malisse | 4-6 6-2 6-0 3-0 RET | | 0.63 | 4.3% | 2.2% | 50.5% | 53.2% | 34.8% | 9/17 | 1:47 |
| 13‑Jan‑2003 | Australian Open | Hard | R64 | 23 | 70 | (20)Malisse d. Antony Dupuis [FRA] | 6-3 5-7 7-6(6) 7-5 | | 1.06 | 14.1% | 3.9% | 46.1% | 79.7% | 66.7% | 3/6 | 2:52 |
| 13‑Jan‑2003 | Australian Open | Hard | R128 | 23 | 44 | (20)Malisse d. Dominik Hrbaty [SVK] | 6-2 6-3 6-2 | | 1.58 | 5.2% | 6.5% | 39.0% | 86.7% | 55.3% | 2/4 | 1:37 |
| 6‑Jan‑2003 | Sydney | Hard | R32 | 25 | 44 | Max Mirnyi [BLR] d. Malisse | 7-6(5) 6-7(5) 6-3 | | 0.91 | 10.2% | 6.8% | 61.9% | 69.9% | 48.9% | 11/15 | 2:06 |