| 28‑Jun‑2021 | Wimbledon | Grass | QF | 8 | 18 | (14)Hubert Hurkacz [POL] d. (6)Federer | 6-3 7-6(4) 6-0 | (ch) | 0.68 | 5.4% | 3.2% | 64.5% | 66.7% | 33.3% | 10/15 | 1:49 |
| 20‑Jan‑2020 | Australian Open | Hard | SF | 3 | 2 | (2)Novak Djokovic [SRB] d. (3)Federer | 7-6(1) 6-4 6-3 | (ch) | 0.76 | 14.4% | 2.9% | 65.4% | 66.2% | 41.7% | 7/11 | 2:18 |
| 27‑May‑2019 | Roland Garros | Clay | SF | 3 | 2 | (2)Rafael Nadal [ESP] d. (3)Federer | 6-3 6-4 6-2 | (ch) | 0.72 | 3.2% | 1.1% | 59.1% | 61.8% | 39.5% | 10/16 | 2:25 |
| 27‑Jun‑2016 | Wimbledon | Grass | QF | 3 | 13 | (3)Federer d. (9)Marin Cilic [CRO] | 6-7(4) 4-6 6-3 7-6(9) 6-3 | (ch) | 1.06 | 16.0% | 0.0% | 62.7% | 79.2% | 58.7% | 7/8 | 3:17 |
| 18‑Jan‑2016 | Australian Open | Hard | SF | 3 | 1 | (1)Novak Djokovic [SRB] d. (3)Federer | 6-1 6-2 3-6 6-3 | (ch) | 0.61 | 5.0% | 1.0% | 57.0% | 61.4% | 48.8% | 4/9 | 2:19 |
| 24‑May‑2015 | Roland Garros | Clay | QF | 2 | 9 | (8)Stan Wawrinka [SUI] d. (2)Federer | 6-4 6-3 7-6(4) | (ch) | 0.65 | 6.3% | 0.0% | 63.4% | 67.6% | 56.1% | 5/8 | 2:09 |
| 19‑Jan‑2015 | Australian Open | Hard | R32 | 2 | 46 | Andreas Seppi [ITA] d. (2)Federer | 6-4 7-6(5) 4-6 7-6(5) | (ch) | 1.06 | 10.9% | 6.5% | 59.4% | 80.5% | 48.2% | 2/5 | 2:57 |
| 21‑Nov‑2014 | Davis Cup WG F: FRA vs SUI | Clay | RR | 2 | 19 | Gael Monfils [FRA] d. Federer | 6-1 6-4 6-3 | | | | | | | | | |
| 25‑Aug‑2014 | US Open | Hard | SF | 3 | 16 | (14)Marin Cilic [CRO] d. (2)Federer | 6-3 6-4 6-4 | (ch) | 0.71 | 14.3% | 1.2% | 61.9% | 69.2% | 50.0% | 4/8 | 1:45 |
| 25‑Aug‑2014 | US Open | Hard | QF | 3 | 24 | (2)Federer d. (20)Gael Monfils [FRA] | 4-6 3-6 6-4 7-5 6-2 | (ch) | 1.24 | 3.3% | 1.3% | 57.0% | 75.6% | 56.9% | 10/15 | 3:20 |
| 13‑Jan‑2014 | Australian Open | Hard | SF | 6 | 1 | (1)Rafael Nadal [ESP] d. (6)Federer | 7-6(4) 6-3 6-3 | (ch) | 0.67 | 7.6% | 1.0% | 65.7% | 65.2% | 50.0% | 10/14 | 2:24 |
| 26‑Aug‑2013 | US Open | Hard | R16 | 7 | 22 | (19)Tommy Robredo [ESP] d. (7)Federer | 7-6(3) 6-3 6-4 | (ch) | 1.01 | 5.8% | 0.0% | 60.5% | 73.1% | 47.1% | 3/7 | 2:24 |
| 27‑May‑2013 | Roland Garros | Clay | QF | 3 | 8 | (6)Jo Wilfried Tsonga [FRA] d. (2)Federer | 7-5 6-3 6-3 | (ch) | 0.56 | 0.0% | 3.0% | 67.0% | 58.2% | 42.4% | 8/14 | 1:51 |
| 27‑Aug‑2012 | US Open | Hard | QF | 1 | 7 | (6)Tomas Berdych [CZE] d. (1)Federer | 7-6(1) 6-4 3-6 6-3 | (ch) | 0.83 | 6.1% | 2.6% | 63.5% | 71.2% | 45.2% | 6/11 | 2:42 |
| 25‑Jul‑2012 | London Olympics | Grass | F | 1 | 4 | (3)Andy Murray [GBR] d. (1)Federer | 6-2 6-1 6-4 | (ch) | 0.64 | 11.5% | 1.3% | 65.4% | 64.7% | 37.0% | 5/10 | 1:56 |
| 25‑Jun‑2012 | Wimbledon | Grass | R32 | 3 | 32 | (3)Federer d. (29)Julien Benneteau [FRA] | 4-6 6-7(3) 6-2 7-6(6) 6-1 | | 1.28 | 9.0% | 2.6% | 64.7% | 79.2% | 56.4% | 4/6 | 3:34 |
| 27‑May‑2012 | Roland Garros | Clay | SF | 3 | 1 | (1)Novak Djokovic [SRB] d. (3)Federer | 6-4 7-5 6-3 | (ch) | 0.72 | 10.5% | 3.5% | 55.8% | 56.3% | 44.7% | 3/10 | 2:05 |
| 27‑May‑2012 | Roland Garros | Clay | QF | 3 | 9 | (3)Federer d. (9)Juan Martin Del Potro [ARG] | 3-6 6-7(4) 6-2 6-0 6-3 | (ch) | 1.26 | 8.0% | 0.7% | 58.0% | 68.8% | 60.3% | 6/10 | 3:14 |
| 22‑May‑2011 | Roland Garros | Clay | F | 3 | 1 | (1)Rafael Nadal [ESP] d. (3)Federer | 7-5 7-6(3) 5-7 6-1 | (ch) | 0.92 | 8.7% | 0.8% | 63.5% | 68.8% | 39.1% | 8/15 | 3:40 |
| 17‑Jan‑2011 | Australian Open | Hard | SF | 2 | 3 | (3)Novak Djokovic [SRB] d. (2)Federer | 7-6(3) 7-5 6-4 | (ch) | 0.97 | 4.8% | 0.0% | 59.0% | 72.6% | 46.5% | 9/14 | 3:00 |
| 21‑Jun‑2010 | Wimbledon | Grass | R128 | 2 | 60 | (1)Federer d. Alejandro Falla [COL] | 5-7 4-6 6-4 7-6(1) 6-0 | (ch) | 1.27 | 13.9% | 4.6% | 58.9% | 78.7% | 54.8% | 7/10 | 3:18 |
| 25‑May‑2009 | Roland Garros | Clay | R16 | 2 | 63 | (2)Federer d. Tommy Haas [GER] | 6-7(4) 5-7 6-4 6-0 6-2 | (ch) | 1.56 | 12.3% | 0.8% | 63.1% | 85.4% | 60.4% | 3/5 | 3:07 |
| 19‑Jan‑2009 | Australian Open | Hard | R16 | 2 | 21 | (2)Federer d. (20)Tomas Berdych [CZE] | 4-6 6-7(4) 6-4 6-4 6-2 | (ch) | 1.05 | 12.6% | 3.1% | 67.9% | 70.4% | 47.1% | 7/12 | 3:25 |
| 23‑Jun‑2008 | Wimbledon | Grass | F | 1 | 2 | (2)Rafael Nadal [ESP] d. (1)Federer | 6-4 6-4 6-7(5) 6-7(8) 9-7 | (ch) | 1.02 | 12.8% | 1.0% | 65.1% | 72.4% | 57.4% | 9/13 | 4:48 |
| 25‑May‑2008 | Roland Garros | Clay | F | 1 | 2 | (2)Rafael Nadal [ESP] d. (1)Federer | 6-1 6-3 6-0 | (ch) | 0.52 | 2.6% | 0.0% | 68.8% | 49.1% | 20.8% | 9/17 | 1:48 |
| 14‑Jan‑2008 | Australian Open | Hard | SF | 1 | 3 | (3)Novak Djokovic [SRB] d. (1)Federer | 7-5 6-3 7-6(5) | (ch) | 0.85 | 9.2% | 1.8% | 62.4% | 70.6% | 43.9% | 7/11 | 2:26 |
| 21‑Mar‑2005 | Miami Masters | Hard | F | 1 | 31 | (1)Federer d. (29)Rafael Nadal [ESP] | 2-6 6-7(4) 7-6(5) 6-3 6-1 | (ch) | 1.08 | 6.0% | 6.0% | 59.6% | 74.4% | 49.2% | 4/9 | 3:43 |
| 24‑May‑2004 | Roland Garros | Clay | R32 | 1 | 30 | (28)Gustavo Kuerten [BRA] d. (1)Federer | 6-4 6-4 6-4 | (ch) | 0.82 | 10.5% | 2.1% | 63.2% | 68.3% | 48.6% | 8/12 | 2:04 |
| 26‑May‑2003 | Roland Garros | Clay | R128 | 5 | 88 | Luis Horna [PER] d. (5)Federer | 7-6(6) 6-2 7-6(3) | | 0.84 | 9.7% | 3.9% | 57.3% | 76.3% | 40.9% | 4/8 | 2:11 |
| 5‑May‑2003 | Rome Masters | Clay | F | 5 | 47 | Felix Mantilla [ESP] d. (4)Federer | 7-5 6-2 7-6(8) | (ch) | 0.99 | 7.7% | 6.7% | 49.0% | 68.6% | 49.1% | 5/11 | 2:41 |
| 26‑Aug‑2002 | US Open | Hard | R16 | 13 | 34 | (32)Max Mirnyi [BLR] d. (13)Federer | 6-3 7-6(5) 6-4 | | 0.77 | 4.3% | 4.3% | 51.6% | 72.9% | 62.2% | 5/7 | 1:52 |
| 24‑Jun‑2002 | Wimbledon | Grass | R128 | 9 | 154 | (Q)Mario Ancic [CRO] d. (7)Federer | 6-3 7-6(2) 6-3 | (ch) | 0.73 | 1.2% | 9.3% | 54.7% | 76.6% | 46.2% | 3/6 | 1:40 |
| 27‑May‑2002 | Roland Garros | Clay | R128 | 8 | 45 | Hicham Arazi [MAR] d. (8)Federer | 6-3 6-2 6-4 | | 0.70 | 5.9% | 4.7% | 50.6% | 67.4% | 35.7% | 8/14 | 1:35 |
| 18‑Mar‑2002 | Miami Masters | Hard | F | 14 | 10 | (9)Andre Agassi [USA] d. (12)Federer | 6-3 6-3 3-6 6-4 | (ch) | 1.00 | 9.0% | 2.7% | 62.2% | 65.2% | 59.5% | 7/13 | 2:21 |
| 22‑Oct‑2001 | Basel | Carpet | F | 13 | 11 | (2)Tim Henman [GBR] d. (4)Federer | 6-3 6-4 6-2 | (ch) | 0.75 | 2.2% | 2.2% | 56.0% | 68.6% | 47.5% | 3/7 | 1:55 |
| 27‑Aug‑2001 | US Open | Hard | R16 | 13 | 2 | (2)Andre Agassi [USA] d. (13)Federer | 6-1 6-2 6-4 | (ch) | 0.63 | 1.7% | 3.4% | 47.5% | 60.7% | 48.4% | 1/6 | 1:23 |
| 25‑Jun‑2001 | Wimbledon | Grass | QF | 15 | 11 | (6)Tim Henman [GBR] d. (15)Federer | 7-5 7-6(6) 2-6 7-6(6) | (ch) | 0.95 | 8.0% | 1.3% | 60.7% | 75.8% | 49.2% | 6/9 | 3:13 |
| 28‑May‑2001 | Roland Garros | Clay | QF | 18 | 13 | (13)Alex Corretja [ESP] d. Federer | 7-5 6-4 7-5 | (ch) | 0.94 | 1.9% | 4.8% | 66.3% | 60.9% | 42.9% | 10/17 | 2:41 |
| 28‑May‑2001 | Roland Garros | Clay | R64 | 18 | 115 | Federer d. Sargis Sargsian [ARM] | 4-6 3-6 6-2 6-4 9-7 | | 1.17 | 6.1% | 1.4% | 66.0% | 72.2% | 60.0% | 7/10 | 3:17 |
| 15‑Jan‑2001 | Australian Open | Hard | R32 | 29 | 18 | (15)Arnaud Clement [FRA] d. Federer | 7-6(5) 6-4 6-4 | | 0.74 | 11.0% | 8.5% | 62.7% | 64.9% | 40.9% | 6/11 | 2:08 |
| 28‑Aug‑2000 | US Open | Hard | R32 | 40 | 12 | (12)Juan Carlos Ferrero [ESP] d. Federer | 7-5 7-6(6) 1-6 7-6(6) | (ch) | 1.19 | 10.4% | 5.2% | 55.6% | 80.0% | 50.0% | 8/12 | 2:53 |
| 26‑Jun‑2000 | Wimbledon | Grass | R128 | 35 | 5 | (5)Yevgeny Kafelnikov [RUS] d. Federer | 7-5 7-5 7-6(6) | (ch) | 0.94 | 8.7% | 1.7% | 58.3% | 64.2% | 58.3% | 2/7 | 2:08 |
| 29‑May‑2000 | Roland Garros | Clay | R16 | 54 | 10 | (10)Alex Corretja [ESP] d. Federer | 7-5 7-6(7) 6-2 | (ch) | 0.73 | 7.1% | 4.8% | 58.7% | 71.6% | 34.6% | 9/14 | 2:36 |
| 17‑Jan‑2000 | Australian Open | Hard | R32 | 62 | 54 | Arnaud Clement [FRA] d. Federer | 6-1 6-4 6-3 | | 0.66 | 8.0% | 6.8% | 55.7% | 65.3% | 33.3% | 6/12 | 1:41 |
